Ion channel TRPV2 is critical in enhancing B cell activation and function.
Li C, Zhao M, Liu X, Li Y, Xu B, Zhou L, Sun X, Sun W, Kang N, Ji Z, Li T, An H, Wang F, Wu C, Ye JY, Zhang JR, Wang Q, Zhao X, Li Z, Liu W.
Li C, et al.
J Exp Med. 2024 Mar 4;221(3):e20221042. doi: 10.1084/jem.20221042. Epub 2024 Feb 14.
J Exp Med. 2024.
PMID: 38353705
Physiologically, TRPV2 expression level is positively correlated to influenza-specific antibody production and is low in newborns and seniors. ...Correspondingly, mice with deficient TRPV2 in B cells display impaired antibody responses following immunization. ...
Physiologically, TRPV2 expression level is positively correlated to influenza-specific antibody production and is low in newborns and …